Maternal Vsx1 plays an essential role in regulating prechordal mesendoderm and forebrain formation in zebrafish
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LYMPHOID NEOPLASIA HDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma
In Hodgkin lymphoma (HL), the malignant cells are surrounded by a large number of reactive infiltrating inflammatory cells, including OX40-expressing T cells and interleukin 10 (IL-10)–producing regulatory T (T-reg) cells. These T-reg cells can suppress the immune response and thus contribute to the maintenance of immune tolerance and to insufficient antitumor response. The engagement of OX40L ...
متن کاملHDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma.
In Hodgkin lymphoma (HL), the malignant cells are surrounded by a large number of reactive infiltrating inflammatory cells, including OX40-expressing T cells and interleukin 10 (IL-10)-producing regulatory T (T-reg) cells. These T-reg cells can suppress the immune response and thus contribute to the maintenance of immune tolerance and to insufficient antitumor response. The engagement of OX40L ...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 2014
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2014.08.011